| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_faf4f62077d00715d8906872656dade6 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-522
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K2039-523
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A50-30 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-255
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K39-0275 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-39
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K39-112
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-36
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N1-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-255 |
| filingDate |
2017-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4a92c1c420f4c0f84fc4b1709bd77242 |
| publicationDate |
2019-06-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3495469-A1 |
| titleOfInvention |
Vaccine compositions ii |
| abstract |
The present invention provides a genetically engineered non-natural bacterium comprising inactivating mutations in one or more genes selected fromandwherein the bacterium is derived fromspp, in particular Salmonella enterica, such asTyphi,Paratyphi A,Paratyphi B orParatyphi C. The one or more inactivating mutations may comprise the partial or complete deletion of the one or more genes selected fromandThe non-natural bacterium of the invention is provided for use in the treatment or prevention of a disease, such as an infectious disease or cancer. For example the bacterium may be for use in vaccination against a disease, such as typhoid or paratyphoid enteric fever. The bacterium may also be used as an anti-cancer vaccine comprising suitable antigens. |
| priorityDate |
2017-12-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |