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filingDate 2017-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_0f8ac383f9a2274c4fef276a0a080237
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b91a5f05cd7d274a8085447df7598a3c
publicationDate 2019-05-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3482199-A1
titleOfInvention A universal assay for determining the quantity of therapeutic monoclonal antibodies and their corresponding anti-drug-antibodies in samples
abstract The present invention relates to a kit of parts and methods for determining the presence and quantity of one or more therapeutic monoclonal antibody drugs and/or therapeutic monoclonal antibody inhibitor drug antibodies in a biological sample, the method comprising the steps of providing a reaction liquid comprising the sample, a first conjugate comprising the target of the therapeutic monoclonal antibody and a first conjugated moiety and a second conjugate comprising the target of the therapeutic monoclonal antibody and a second conjugated moiety, followed by detecting the change in spectrophotometric signal when the complex between the therapeutic monoclonal antibody drug, the first conjugate and a the second conjugate forms.
priorityDate 2016-07-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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