Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_90e56f22ea801271c3f1fa56f6ed63c7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0652 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0433 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0647 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0424 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2200-0668 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2469-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-087 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2300-0864 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L2400-0454 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-558 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01L3-502761 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N35-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12M1-24 |
filingDate |
2014-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e05675e65d0dfa80c85958a8392c3483 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_13459c804f366b1f6fe51af743a575e4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_649e97922b8abda309f6dd1ff51388d2 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d82ec06753fc7659c701ca6b89016954 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_61c63783afec1bc459fb01a35017b585 |
publicationDate |
2019-04-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3473700-A1 |
titleOfInvention |
Microfluidic devices having isolation pens and methods of testing biological micro-objects with same |
abstract |
A microfluidic device can comprise at least one swept region that is fluidically connected to unswept regions. The fluidic connections between the swept region and the unswept regions can enable diffusion but substantially no flow of media between the swept region and the unswept regions. The capability of biological micro-objects to produce an analyte of interest can be assayed in such a microfluidic device. Biological micro-objects in sample material loaded into a microfluidic device can be selected for particular characteristics and disposed into unswept regions. The sample material can then be flowed out of the swept region and an assay material flowed into the swept region. Flows of medium in the swept region do not substantially affect the biological micro-objects in the unswept regions, but any analyte of interest produced by a biological micro-object can diffuse from an unswept region into the swept region, where the analyte can react with the assay material to produce a localized detectable reaction. Any such detected reactions can be analyzed to determine which, if any, of the biological micro-objects are producers of the analyte of interest. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11473081-B2 |
priorityDate |
2013-10-22-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |