| abstract |
Provided is a method for amidating a hydroxy ester compound at a high chemical selectivity. The amidation reaction method for a hydroxy ester compound comprises, in the presence of a catalyst containing a compound of a transition metal of the group 4 or group 5 in the periodic table, reacting at least one kind of hydroxy ester compound selected from the group consisting of an ±-hydroxy ester compound, a ²-hydroxy ester compound, a ³-hydroxy ester compound and a ´-hydroxy ester compound with an amino compound so as to amidate an ester group having a hydroxyl group at the ±-, ²-, ³- or ´-position of the hydroxy ester compound. |