| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_73b46a19d9635f31a98d8919333159f4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-10056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-30024
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-20036
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T2207-20076 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5026
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06T7-0012
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6875 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06T7-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-50 |
| filingDate |
2017-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a513a46c867a78383d2140ea80403bcc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8d11cc94ef2a3add31f145e1fc9f9506
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3eaa24c0d20f43fdfc85616c92ad86fe
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6abef72e243124e6b7aa4c0e05911338 |
| publicationDate |
2019-03-13-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3452985-A2 |
| titleOfInvention |
Nucleolar structure evaluation and manipulation |
| abstract |
The nucleolus is a potent disease biomarker and a target in for instance cancer therapy. The present invention relates to how depletion of each of the eighty human r-proteins affects nucleolar structure, pre-rRNA processing, mature rRNA accumulation and p53 steady-state level. The present invention further relates to an image -processing program for qualitative and quantitative discrimination of normal from altered nucleolar morphology. |
| priorityDate |
2016-05-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |