http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3448148-A1

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publicationDate 2019-03-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3448148-A1
titleOfInvention Indicator stem cell line/living organism (non-human) and a method for detection of the genotoxic potential of aquatic samples or aqueous solutions of test compounds
abstract Indicator stem cell line/transgenic (non-human) living organism for non-destructive, self-signalizing visualization of nuclear structures, which allows the identification of nuclear and chromosome anomalies - including micronuclei -as consequence of exposure to genotoxic compounds, wherein the stem cell line is a transgenic stem cell line from a (non- human) animal with nuclei labelled with a fluorescent protein fused to a chromatin-associated protein and/or the living organism is a transgenic (non-human) living organism in which a cell lineage has nuclei labelled with a fluorescent protein fused to a chromatin-associated protein.
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