| abstract |
Provided is a peptide having an ability to inhibit binding between amylospheroids (ASPD) and neurons. In one aspect, provided is a synthesized, isolated, or purified polypeptide represented by Formula (I) or (II) below: X 1 X 2 X 3 X 4 (I), where X 1 is R, H, or K, X 2 is R, K, D, H, W, Q, Y, or T, X 3 is any amino acid, and X 4 is W, F, or Y; and X 1 X 2 X 3 X 4 (II), where X 1 is R, H, or K, X 2 is any amino acid, X 3 is L, G, I, W, R, M, D, E, A, V, or K, and X 4 is W, F, or Y. |