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filingDate 2017-04-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e45e48f5e3b7fbb619b94c7235548b94
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publicationDate 2019-02-13-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3440106-A1
titleOfInvention T cell receptors
abstract The present invention relates to T cell receptors (TCRs) which bind the HLA-A*0201 restricted peptide GVYDGREHTV (SEQ ID NO: 1) derived from the MAGE-A4 protein. The TCRs of the invention demonstrate excellent specificity profiles for this MAGE epitope. Also provided are nucleic acids encoding the TCRs, cells engineered to present the TCRs, cells harbouring expression vectors encoding the TCRs and pharmaceutical compositions comprising the TCRs, nucleic acids or cells of the invention.
priorityDate 2016-04-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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