http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3434322-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dd554226db6acd26c2c6b6051e3b54d6 |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2015-0833 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-0412 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-0806 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N15-088 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N1-327 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-20 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61N1-32 |
| filingDate | 2018-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8ad4593da7bc694c7be61332292b3076 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aa2cb5a4ebf35d0c5b8fe9f570112dfd |
| publicationDate | 2019-01-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3434322-A1 |
| titleOfInvention | Method and system for in-silico design of skin electroporation |
| abstract | A system and method for testing of skin electroporation using simulations of human skin has been described. The system is using a simulation protocol to provide an in-silico design of skin's upper layer stratum-corneum (SC) at molecular level. This model is then further used to design the skin electroporation strategy. An external electric field was applied across the lipid bilayer to form a pore in the lipid bilayer. The pore size and pore growth rate was calculated depending on the applied external electric field. The generated pore was then stabilized by varying the external electric field. Further, on removing the external electric field, the reformation of lipid bilayer and self-healing of human skin was also achieved. In another embodiment, the system is also configured to perform the virtual testing of a drug permeation through skin in presence of an external electric field. |
| priorityDate | 2017-07-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 28.