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filingDate 2017-03-07-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3431587-A1
titleOfInvention Method for producing cardiac precursor cell and myocardial cell from pluripotent stem cell
abstract Provided is a method of inducing cardiac progenitor cells or cardiomyocytes from pluripotent stem cells. n The present invention provides a method for producing cardiac progenitor cells from pluripotent stem cells, comprising expressing Tbx6 in the pluripotent stem cells. Moreover, the present invention provides a method for producing cardiomyocytes from pluripotent stem cells, comprising: a step of inducing cardiac progenitor cells from pluripotent stem cells, comprising expressing a Tbx6 gene in the pluripotent stem cells; and a step of inducing cardiomyocytes from the cardiac progenitor cells induced in the above step, comprising suppressing the expression of the Tbx6 gene.
priorityDate 2016-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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