| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_52e932f206ab8bcf8a9c2eb7b5f67db6 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-005
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J31-006
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J71-001
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07J9-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J31-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J71-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07J9-00 |
| filingDate |
2017-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6fd48be2a968d529c04903eef7da3e65
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_933bb41439847cd8b4ad0413912105a6
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_47b066e6122c7ae2003efa87b944c62f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9857af2309145a5d9ff367b7b679b0a7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_770dce5923eeeb68ec974764f0e759cc |
| publicationDate |
2019-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3431486-A1 |
| titleOfInvention |
Process and intermediates for the synthesis of obeticholic acid and derivatives thereof |
| abstract |
The invention relates to a process for the preparation of obeticholic acid and derivatives thereof comprising: n(a) hydrogenation of the double bond and reductive opening of the epoxide of a compound of formula (II) or a salt or solvate thereofn nto obtain a compound of formula (IIIa) and/or (IIIb), or salts or solvates thereofn nand n(b) conversion of a compound of formula (IIIa) and/or a compound of formula (IIIb), or a salt or solvate thereof, into a compound of formula (I), or a salt or solvate thereof |
| priorityDate |
2017-07-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |