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filingDate 2017-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2019-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3431173-A1
titleOfInvention Continuous manufacture of guidance molecule drug conjugates
abstract Described herein is a modification unit (37) for the continuous, germ-reduced processing of a guidance molecule and a linker comprising the following components: n- at least one reservoir containing the guidance molecule in buffer solution (1) and/or at least one inlet for a product stream containing the guidance molecule in buffer solution, n- at least one reservoir containing the linker in solution (2), n- at least one mixing device (3), n- at least two valves (7, 8), one for dosage of the guidance molecule and one for dosage of the linker molecule n- at least one outlet for the product stream comprising the guidance molecule-linker complexes and/or a reservoir for taking up the guidance molecule-linker complexes (5).
priorityDate 2017-07-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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