http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3430548-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4296e3c718c9579ab0ad87c5634f4d47 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e974c8a148aa6bf505c7e049484889e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/Y02A90-10 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H20-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H10-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G06N7-01 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16H10-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G16H20-10 |
| filingDate | 2017-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f368c4145c96155ef54bf296ca77027f http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d69596781a09cac1615d064c4be26de9 |
| publicationDate | 2019-01-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3430548-A1 |
| titleOfInvention | Methods for determining dosing of a therapeutic agent and related treatments |
| abstract | Provided herein are methods employing a toxicity and efficacy probability interval (TEPI) design for performing a clinical trial, such as a Phase I dose-finding trial. In some embodiments, the methods can be used in the dosing of subjects administered a therapy, such as adoptive cell therapy or other immunotherapy, where safety and efficacy data for a therapeutic agent can be observed in the same timeframe or period. In some embodiments, one or more of or all of the steps of the method occur at an electronic device containing one or more processors and memory, such as implemented by a computer. Also provided are methods of administering a therapeutic agent to a subject in accord with the dosing decisions. |
| priorityDate | 2016-03-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 1197.