| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e66dcd041b390d50bd6668a9009a1e6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50ae3c428a3758805e67d8ab7d435e96 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0056
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5047
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2072
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2081
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-2095
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-137
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-14
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-135 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-445
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-136
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-135
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-32
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-20
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-14 |
| filingDate |
2017-02-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_72bef96ccf854949571dde492f45cb1c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7e7eb9d1e2fbb1c0aa5a4fe05ce4f975
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bb7a7400c41fd7445d86090a15c71a54
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_96127a55162dd239ab96bca1018abfe9
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_2693e77e6ee39312e64b17e90819d907
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_314a2611f5ec925ce5a562dfe16fe955
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_16c77a6fc9cdd8884f4a75d580444499 |
| publicationDate |
2019-01-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3421032-A1 |
| titleOfInvention |
Pharmaceutical composition particles, orally disintegrating preparation including same, and method for producing pharmaceutical composition particles |
| abstract |
Provided are pharmaceutical composition particles which are capable of achieving both of masking of an unpalatable taste and improvement in dissolution properties; an orally disintegrating tablet including the pharmaceutical composition particles; and a method for manufacturing the pharmaceutical composition particles. Each of the pharmaceutical composition particles includes: a drug-containing core particle; an intermediate layer containing a gelling swelling substance and coating an outside of the core particle; and an outermost layer containing a water-insoluble substance and coating an outside of the intermediate layer. In addition, the method for manufacturing the pharmaceutical composition particles includes: a pulverization step of pulverizing the gelling swelling substance so as to have an average particle diameter of 15 µm or less; a suspension step of obtaining a suspension by suspending the gelling swelling substance pulverized at the pulverization step in an organic solvent; an intermediate layer formation step of forming an intermediate layer on an outside of a core particle by spraying the suspension obtained at the suspension step onto the core particle containing a drug; and an outer layer formation step of forming an outer layer by coating an outside of the intermediate layer with a water-insoluble substance. |
| priorityDate |
2016-02-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |