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filingDate 2017-02-10-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2018-12-19-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3414553-A2
titleOfInvention Method and apparatus for imaging unsectioned tissue speciments
abstract An apparatus and method for real-time optical imaging of a tissue specimen. The apparatus comprises a primary- imaging system configured to use an illumination source to acquire images of a tissue specimen through one or more spectrally separated channels, and configured to perform optical depth sectioning; an auxiliary imaging system, configured to acquire an auxiliary image of the tissue specimen; a specimen holder having a transparent window therewithin, window, the specimen holder comprising one or more position sensors, wherein the specimen holder is configured to be translatable in the specimen plane; a user input device configured to accept user input, wherein the specimen holder is configured to translate in response to the user input in real-time; a processing unit configured to execute a sequence of instructions on the sequence of images acquired by the primary imaging system, the auxiliary image, and at least one specimen holder position to generate a composite representation of the tissue specimen that includes a representation of ceil nuclei in the specimen; and a display device configured to display the composite representation of the tissue specimen in real-time.
priorityDate 2016-02-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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