abstract |
The invention relates to a method for treating, preventing, inhibiting, ameliorating, or eradicating the pathology and/or symptomology of cryptosporidiosis by administering a therapeutic agent which antagonizes or modulates the activity of phosphatidylinositol- 4-OH kinase (PI4K), a lipid kinase of the cryptosporidium protozoa. In one embodiment, the therapeutic agent is a pyrazolo[1,5-a]pyridine compound of Formula (I), or a pharmaceutically acceptable salt, tautomer, or stereoisomer, thereof, wherein the variables are as defined herein. |