| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_361e779ab94fb0a7a7738acec62ff2f5 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P19-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-22
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-60 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-60
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P19-00 |
| filingDate |
2017-01-05-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39edc2e6d548ff63b4741cef968f43cf
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bd96ea00fdb751018eee875556e046c8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_62e50d222db89c0813ce40cef092ae48
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fd2d9ac7850f55f22d2276e95f3807de
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dbe51a81802d90e27d53eef37f91aa73 |
| publicationDate |
2018-11-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3400022-A1 |
| titleOfInvention |
Controlled-release cnp agonists with low initial npr-b activity |
| abstract |
The present invention relates to a controlled-release CNP agonist from which CNP agonist is released with a release half-life of at least 6 hours under physiological conditions and which controlled-release CNP agonist has an EC 50 that is at least 20-fold higher than the EC 50 of the corresponding free CNP agonist and which released CNP agonist has an EC 50 that is at most 3-fold higher than the EC 50 of the corresponding free CNP agonist; to pharmaceutical compositions comprising said controlled-release CNP agonist; their use; and to methods of treatment. |
| priorityDate |
2016-01-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |