abstract |
The present invention provides, inter alia, compounds of formula (I) capable of inhibiting NF-KB. Pharmaceutical compositions containing and methods of using the compounds for the treatment of e.g. inflammation, autoimmune diseases or cancer are also provided herein. A, B, C and D are independently selected from the group consisting of carbon and nitrogen. X, Y and Z are independently selected from the group consisting of oxygen, sulfur and NRa. |