| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3155069b833b184bcd4ad12f7100dd4c
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_8e0daec85fdd4a4c04e22225e70a5cd9 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-8125 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0019
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0073
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0053 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-81
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-57
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P37-06 |
| filingDate |
2016-12-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b3c68da96d9b0a39dd4e9c06a2f5fb8
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_634d20777784019615ec96c7ad2c38a4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ea056d25b191b3997ffeb064fbbbe8d7 |
| publicationDate |
2018-11-07-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3397274-A1 |
| titleOfInvention |
Methods and uses for alpha-1 antitrypsin or recombinant forms thereof, on steroid-refractory graft versus host disease involving gastrointestinal complications |
| abstract |
Embodiments described herein relate to treating a subject with advanced-stage GvHD with α1-antitrypsin (AAT) or carboxyterminal peptide derivatives thereof or recombinant thereof. In certain embodiments, a subject can include a glucocorticoid-refractory patient having GvHD with gut involvement. In other embodiments, donor subjects of a transplant can be treated with α1-antitrypsin (AAT) or carboxyterminal peptide derivatives thereof or recombinant thereof to reduce graft rejection or GvhD in a recipient subject. |
| priorityDate |
2015-12-31-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |