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filingDate 2016-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b7f13d4f7434c92dd966f7ca5781cb22
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publicationDate 2018-10-31-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3394094-A1
titleOfInvention T cell receptors specific for the ny-eso-1 tumor antigen-hla-a*02 complex
abstract The present invention relates to T cell receptors (TCRs) which bind the HLA-A*02 restricted peptide SLLMWITQC derived from the cancer antigen NY-ESO-1. Said TCRs may comprise mutations within the alpha and/or beta variable domains relative to a native NY-ESO-1 TCR. The TCRs of the invention are particularly suitable for use as novel immunotherapeutic reagents for the treatment of malignant disease.
priorityDate 2015-12-22-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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