Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_709b4a26ef028713f9b302509eb824d7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2458-10 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6816 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-682 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6804 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-5308 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-68 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
filingDate |
2016-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1816a79cba2b80b05697f0c9a2725784 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_426fa089ee2f609b970f9f825fb3237e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7b7ae43c36fc76aa6245e8cb2eae1e77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4082f1eecf274188c9e054fe448f6bb6 |
publicationDate |
2018-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3390667-A1 |
titleOfInvention |
Polymer-based signal amplification for protein and cell detection |
abstract |
The present invention relates generally to compositions, methods and kits for detection of a molecule of interest. The present invention is based, at least in part, on the design of nucleic acid oligonucleotides such that they can be used as molecular building blocks which can be assembled (polymerized) to form a dsDNA polymerization product which can be detected and further, can be disassembled (depolymerized) such that the polymerization product is no longer detectable. The invention can be performed multiple times on the same cell population, and is therefore useful for highly sensitive in situ detection of multiple biomarkers. |
priorityDate |
2015-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |