| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2a819eda0adf22936a52362eeebb9fb4 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-5138
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-385 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-51
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-00 |
| filingDate |
2016-12-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5b221f7774e4928185e166a1c5237c44
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_69b8ea4c98f0e96d1b8097630173d1f1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4332d7bdc56c81b831895cc48d6df393
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_002f592a360b918e47dc37540ca0a80d
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9d0bba7977c05c5e8ce7a006e08277f7 |
| publicationDate |
2018-10-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3389641-A1 |
| titleOfInvention |
Protein nanocapsules with detachable zwitterionic coating for protein delivery |
| abstract |
The invention relates to protein nanocapsules that exhibit material properties that change in different in vivo environments. A zwitterion moiety on the surface of the nanocapsule can protect the protein from opsonization in a first environment, yet uncouples from the protein nanocapsule in a second environment (e.g. at a pH of less than 6.5). In embodiments of the invention, the uncoupled protein nanocarrier is then internalized by mammalian cells (e.g. tumor cells). |
| priorityDate |
2015-12-18-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |