| abstract |
The present disclosure provides a substantially sealed system and methods of use thereof for nucleic acid amplification. Said system includes, for example a base, a nucleic acid amplification reaction vessel, a collection cap, a storage cap and/or a housing. The system reduces contamination before, during and after the amplification reaction. Therefore said system reduces amplification of spurious nucleic acids or amplification products. The present disclosure also provides methods of amplifying nucleic acids using said system. |