Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_966a6c1f382ec9bcb5e3839dfd73e5b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3244ba8390b1f290f4ba36389c82488b |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-50 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-948 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K7-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-54353 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-37 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-6845 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-582 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-37 |
filingDate |
2016-11-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c87f6899f6fcef9fc00fb2c4c90a5a44 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_4e5a411dd88ca2b7d45a47d31536cfe7 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_601d8a05cba445f5d47a572617be0e8b http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_39efce85eb8217ae9daca69ee631c024 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_335b49bf6ac6beb21a60d952dc9ad88d |
publicationDate |
2018-10-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3384041-A1 |
titleOfInvention |
System and method for identification of protease substrates |
abstract |
The present disclosure provides a method of identifying a substrate for a protease including contacting a protease to one of a first array and a second array, each array having the same plurality of features, each feature including at least one sequence linked to a solid support. The at least one sequence includes a candidate protease substrate linked to a reporter. The method further includes contacting a detectable element to each of the arrays to allow binding of the detectable element to the reporter, and detecting first and second signals resulting from binding of the detectable element to the each of the reporters in the first and second arrays. The method further includes comparing the first signal and the second signal to identify a difference in the first signal and the second signal, and identifying at least one candidate protease substrate as a substrate for the protease. |
priorityDate |
2015-11-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |