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filingDate 2016-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6daf050a163e5b6591ce34df2a18f03f
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publicationDate 2018-09-12-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3371604-A1
titleOfInvention An assay to detect and quantitate specific antibodies for various redox forms of hmgb1
abstract The invention relates to the quantitation of specific antibodies for at least one redox form of High mobility group box 1 (HMGB1) contained in a biological sample, in particular human serum and/or Cerebrospinal Fluid (CSF). The invention also relates to an in vitro method for assessing the state of progression of a disease or a disorder in which HMGB1 is involved, to an in vitro method for the identification of predisposition, prognostic or diagnostic biomarkers of a disease or a disorder in which HMGB1 is involved. The invention also relates to a kit to quantitate said specific antibodies for at least one redox form of HMGB1, in particular human HMGB1.
priorityDate 2015-11-03-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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