| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_44c713790ce00813da2e6c6d57a29456 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B2200-07
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B61-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07B53-00 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J27-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C51-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/B01J31-0244
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C57-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07C67-343 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C51-09
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B53-00
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07C57-58
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07B61-00 |
| filingDate |
2016-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9a408b84398fbad6b11957790a59af49
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_5813225da3c739e765ea39136784e7dc
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_32653d51d1fc26bf65980e879e3c2f6f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_a1ee2c0e90eb9d5343f5593640daf425
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_271f01de65297daaee5067f8e1662d38
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d8e37c655f9b9070ea35a004a13d7f79
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc4c85ffd22bd723ff1486f63516259f
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f97771ef44c2d29814b0fb2058d11a00 |
| publicationDate |
2018-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3357901-A1 |
| titleOfInvention |
Method for producing optically active 2-(2-fluorobiphenyl-4-yl) propanoic acid |
| abstract |
A novel process for producing optically active 2-(2-fluorobiphenyl-4-yl)propanoic acid is disclosed. This production process is characterized in that a compound of formula [1] is reacted with magnesium and so forth to prepare an organometallic reagent, which is reacted with a compound of formula [2] in the presence of a catalytic amount of a nickel compound and a catalytic amount of an optically active compound of formula [3] to obtain a compound represented by formula [4] which is subsequently converted to a compound represented by formula [5] or a pharmaceutically acceptable salt thereof. |
| priorityDate |
2015-09-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |