Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e41eefe437d41c6b293dbdc3abd7297f |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-7105 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-7105 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K45-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2016-09-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12dfe6d230d0f7ef307614a730aa4f6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c6c1375955dcd2177f21909d2ac2d931 |
publicationDate |
2018-08-08-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3357498-A1 |
titleOfInvention |
Method for suppressing tumors by mir-200 family inhibition |
abstract |
Tumor growth was found to be significantly suppressed in vivo by inhibiting both miRNA containing 5'-AACACUG-3' as a seed sequence and miRNA containing 5'-AAUACUG-3' as a seed sequence. The inhibition significantly altered the proportion of subpopulations of tumor cells and reduced the tumorigenicity in all subpopulations. The inhibition also exerted a remarkable tumor-shrinking effect on already-formed tumors. The present invention provides novel therapeutic potential against tumor. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3597197-A4 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11479769-B2 |
priorityDate |
2015-09-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |