Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_6e29526f284c0155fd79806c9dd5a1c7 |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0066 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0058 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P11-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-113 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-0016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-11 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-53 |
filingDate |
2016-11-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1e9c154630ce9b722404e73595858f77 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3749e1769d9619a671b462f7f52305f1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f7660ac46c6dfb3e96263d4bdbdf05fd http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_caeb4cf50401f2549f9a500dda15ce30 |
publicationDate |
2018-08-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3352799-A2 |
titleOfInvention |
A method effective to modulate expression of t-box protein 4 (tbx4) for reducing progression of lung fibrosis after a lung injury |
abstract |
The described invention provides a method for reducing progression of lung fibrosis after a lung injury comprising administering a therapeutic amount of a therapeutic agent, wherein the therapeutic amount is effective: (a) to modulate expression of a T-box transcription factor in a population of cells in lung; and (b) to reduce proliferation of the population of cells in lung expressing the T-box transcription factor. According to some embodiments the T-box transcription factor is Tbx4. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11725056-B2 |
priorityDate |
2015-09-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |