http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3335735-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dcf46c8bf7d75dc4dcc44ac30fcf3e79 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-28 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-4925 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-192 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-19 |
| filingDate | 2013-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f928701118eafc7ff0acc2070dd6d696 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_875f07ba6ea603c919bab626b23b3a17 |
| publicationDate | 2018-06-20-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3335735-A1 |
| titleOfInvention | Methods of administering and evaluating nitrogen scavenging drugs for the treatment of hepatic encephalopathy |
| abstract | The present disclosure provides methods for treating hepatic encephalopathy (HE) and for optimizing and adjusting nitrogen scavenging drug dosage for subjects with HE, comprising administering a nitrogen scavenging drug at a dosage sufficient to maintain a fasting blood ammonia level at or below a specified threshold level which is 1.5 times the upper limit of normal for blood ammonia. The nitrogen scavenging drug administered in the method is a phenylacetic acid prodrug selected from HPN-100, PBA, NaPBA, sodium benzoate, or any combination thereof (i.e. any combination of two or more of HPN-100, PBA, NaPBA). |
| priorityDate | 2012-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 59.