http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3326091-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a394534c733653b0f1eec3e043efdd13 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_e0e1a688865f67ed42813417aebafcf3 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H70-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G16H50-50 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G06F19-00 |
| filingDate | 2016-07-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f3b7759a480d75cd0725239b1f3cf232 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_9ea1490c0bbdc865f446fd09dd7c34e6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_48fbb93f88cf38a87b97fd4fe75c36b1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_c60abe0de7962325d5842de7ab481199 |
| publicationDate | 2018-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3326091-A1 |
| titleOfInvention | Methods of modelling interactions between biomarkers |
| abstract | The present invention provides a method of modelling the interaction between different biomarkers or other patient measurements and their progression along the trajectory of a neurodegenerative disease, the method comprising the steps of:a) obtaining longitudinal biomarker profiles from multiple subjects by measuring one or more predetermined biomarkers over time;b) storing said longitudinal biomarker profiles in a first memory; c) using a computer system to perform temporal alignment of said longitudinal biomarker profiles;d) defining a parametric model for eachof said one or more biomarkers;e) fitting an appropriate parametric model to each longitudinal biomarker profile for each subject;g) defining a biomarker signature for each longitudinal biomarker profile;and h) forming a global disease model by combining individual parametric models and biomarker signatures. |
| priorityDate | 2015-07-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
| Predicate | Subject |
|---|---|
| isDiscussedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/substance/SID419570135 http://rdf.ncbi.nlm.nih.gov/pubchem/compound/CID170049 |
Total number of triples: 18.