| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_2ff57144603c661f4b368824eae0729f |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-85 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-47 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07K14-47
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-85 |
| filingDate |
2016-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8b98a3d65cb2feff24926869dad8344a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_89cc720ea804330f050eeebeaeee68d7
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1a4e41ccb5c0725bc3c900b6aebcc6e3
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e1fb946ea5f73b61ae8fb57881c008e5 |
| publicationDate |
2018-05-23-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3323826-A1 |
| titleOfInvention |
Native chinese hamster ovary cell secretion signal peptides for production of recombinant polypeptides |
| abstract |
The invention provides a genetically modified Chinese Hamster Ovary (CHO) cell for production of a recombinant polypeptide, comprising a transgene encoding a CHO-derived signal peptide fused to a recombinant polypeptide, wherein said signal peptide is capable of directing co-translational transport of said polypeptide in the cell resulting in enhanced levels of polypeptide secretion. The invention further provides a method for producing a recombinant polypeptide by using the genetically modified CHO cell. The invention further provides for the use of a CHO-derived signal peptide and a transgene encoding said signal peptide to enhance production of extracellular recombinant polypeptide by a genetically modified CHO cell. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020183269-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020183270-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/WO-2020183271-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4063379-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-4007579-A4
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-2030084-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-2030083-A1
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-544000-C2
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/SE-544001-C2 |
| priorityDate |
2016-11-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |