abstract |
The present invention relates to a test support method for supporting the prediction of pathological complete response (pCR) to preoperative therapy in breast cancer by using a human breast cancer tissue section, and the test support method includes Step [1]: the step of acquiring a fluorescence image of the breast cancer tissue section, which fluorescence image shows bright spots of fluorescent nanoparticles labeling two or more kinds of breast cancer-related proteins including at least HER2; Step [2]: the step of acquiring numerical values representing the expression levels of each of the two or more kinds of breast cancer-related proteins including HER2 on the basis of the bright spots of the fluorescence image, and calculating, as an index, the value of a ratio of numerical value representing the expression level of HER2/numerical value representing the expression level of a breast cancer protein other than HER2; and Step [3]: the step of acquiring information for predicting pCR by performing an analysis using the value of the ratio. |