Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_46cb3dfdd38a34ce27bf0e2323d90a6a http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_fbb16b39443f72f271c474607c90fced |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-95 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y503-03002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2330-51 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K2319-24 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P19-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-52 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-63 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N1-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P21-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P5-026 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12P7-64 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07K14-395 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-65 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-635 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P21-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P19-62 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P5-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12P7-64 |
filingDate |
2016-06-24-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f164d356f1419216cdea579fdd12f0e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7c6cc1e0850129c8c74664073f6da2c6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e12c3b74b775691d4f43cbaa1ffe03b6 |
publicationDate |
2018-05-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3313996-A1 |
titleOfInvention |
Maltose dependent degrons, maltose-responsive promoters, stabilization constructs, and their use in production of non-catabolic compounds |
abstract |
The present disclosure relates to the use of a maltose dependent degron to control stability of a protein of interest fused thereto at the post-translational level. The present disclosure also relates to the use of a maltose dependent degron in combination with a maltose-responsive promoter to control gene expression at the transcriptional level and to control protein stability at the post-translational level. The present disclosure also relates to the use of a stabilization construct that couples expression of a cell-growth-affecting protein with the production of non-catabolic compounds. The present disclosure further relates to the use of a synthetic maltose-responsive promoter. The present disclosure further provides compositions and methods for using a maltose dependent degron, a maltose-responsive promoter, and a stabilization construct, either alone or in various combinations, for the production of non-catabolic compounds in genetically modified host cells. |
isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3313995-B1 http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-10808015-B2 |
priorityDate |
2015-06-25-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |