Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_4d2a1c2ecad0081ae2c7efc988b1474c |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-6903 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-61 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-20 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08J3-075 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C08L5-08 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K47-36 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P35-00 |
filingDate |
2016-05-30-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d7ee5a70f8a4e0208ea68161c9fdb85 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7d4a9ce141be07498454932732ed8f22 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12a49dbe105ff62da72c65ef696245c4 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94f1aafc1717ccb2cc5d7e9421f0bec7 |
publicationDate |
2018-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3302569-A1 |
titleOfInvention |
Cross-linked hyaluronic acid for drug delivery and pharmaceutical preparation using same |
abstract |
A water-soluble gel polymer matrix comprising hyaluronic acid and an antitumor agent is described herein. The antitumor agent is crosslinked with the hyaluronic acid by at least one of covalent and/or non-covalent bonding resulting in improved water solubility of the antitumor agent. Pharmacokinetic studies illustrated that the antitumor agent exhibits enhanced C max (maximum drug plasma concentration) and T max (time required to reach C max ) values. |
priorityDate |
2015-05-29-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |