Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_a7dfb0281008cb570feea037cd350c8f http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_dbdae384a9f1ad0588422c89ddc71a00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_00a421ab71bd49a451d0a49d23a082c7 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-4886 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Y304-24087 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P9-00 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K38-48 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61P9-10 |
filingDate |
2016-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_99958134a35017f0ee2c631716ff4b97 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_7705561e19cee5057256328752c7d6d8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_b711a33550d1e755cecd9cb44145ccb3 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_bc2c1a1bb4f5bd885e3dc288c80df938 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_cc4ae9afc44d8337603ce16d9c8b484e |
publicationDate |
2018-04-11-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3302533-A1 |
titleOfInvention |
Compositions comprising adamts13 for use in methods for the recanalization of occluded blood vessels in an infarction |
abstract |
Provided herein are methods for recanalization of occluded blood vessels in a subject having an infarction. The method includes a step of administering to the subject a therapeutically effective amount of isolated ADAMTS13 protein at particular dosages and ranges of times after detection of the infarction. As described herein, ADAMTS13 advantageously recanalizes occluded blood vessels and reduces infarction size, even when administered a prolonged period after stable occlusion. Accordingly, such methods and compositions are useful for the treatment of infractions caused by blood vessel occlusion. |
priorityDate |
2015-05-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |