http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3301103-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_36b8402faef868b9530993bab6e10e6e |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G75-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08G65-34 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H13-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-067 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H23-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07H1-00 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-167 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07H19-067 |
| filingDate | 2016-04-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_6f0a48dc2b3d5a63173a5d97d154cce1 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f5587cfe0c798902df493a86e10e986d http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_aac1faac68bb1094ed8a66f06275e321 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_27629a68b3ed9efd59be33f5595b21fc |
| publicationDate | 2018-04-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3301103-A1 |
| titleOfInvention | Method for producing glycoside compounds |
| abstract | The present invention provides a production method of the glycoside compound represented by the formula (I) or a salt thereof, which includes a step of subjecting a thioether compound represented by the formula (103) and an alcohol compound represented by the formula (105) to a coupling reaction in the presence of a halogenating agent, a desiccant and a Lewis acid, and then distillation in the presence of at least one kind of additive selected from a sulfur-containing antioxidant and a maleimide group-containing compound to give a thioether compound represented by the formula (104) (Step 0); and na step of subjecting a glycoside compound represented by the formula (Ia) and a thioether compound represented by the formula (104) to a coupling reaction in the presence of a halogenating agent, a desiccant and a Lewis acid to give a glycoside compound represented by the formula (Ib) (Step 1). By this method, a phosphoramidite preferable for the production (synthesis) of a nucleic acid can be produced more efficiently at a high purity (each compound is as defined in the DESCRIPTION). |
| priorityDate | 2015-04-02-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 329.