Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_9c8ee440d2758f894babeab7a24ca8cc |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-14 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-31 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-1016 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N2005-1098 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K41-0038 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61N5-1001 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-1135 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K48-005 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-713 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K41-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-713 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K48-00 |
filingDate |
2016-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_06be27343298eddb3001a1295f71b229 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_8a75b0b188abde577d47deb17692412a http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d70fe434b4144fb65a0ca516e09a5650 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_78974e630ce5c68f6bcd861e1ac01865 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_94f9161cbfccad0f5a87e19550e0f901 |
publicationDate |
2018-03-21-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3295960-A1 |
titleOfInvention |
Composition for cancer cell sensitization containing as active ingredient substance inhibiting expression of oncogene of hpv virus |
abstract |
The present invention relates to a composition for cancer cell sensitization containing as an active ingredient a substance inhibiting the expression of an oncogene of a HPV virus, and more specifically, to a composition for radiosensitization which is used for the treatment of cancer induced by HPV infection and contains as an active ingredient oligonucleotide having any one nucleic acid sequence selected from the group consisting of sequence numbers 1 to 10. The oligonucleotide of the present invention inhibits the expressions of E6 and E7 which are HPV virus oncoproteins, thereby inhibiting the proliferation of tumor cells, and enhances the sensitivity of tumor cells to radiation, thereby exhibiting an excellent effect as a sensitizer that can maximize the cell death effect. |
priorityDate |
2015-05-12-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |