| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_3868745a86f52a211bd9026c293ebae8 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-106
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2320-10
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2310-141
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-158
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q2600-178 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N15-111
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12Q1-6883 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12N15-113
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C12Q1-68 |
| filingDate |
2016-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_472bae2524a200820db7519cbe931b02
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_15a34285fc7213a191bded3cbcc9bef1
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_3208d9613b64a7c7354d0719cd34e37a
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_e6cdbe70c5dd7d61c9dd3a08aa234cbb |
| publicationDate |
2018-03-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3292213-A1 |
| titleOfInvention |
Biomarkers for the detection of aspirin insensitivity |
| abstract |
The invention provides a method for determining whether a patient is sensitive or insensitive to a treatment with a thromboxane A2 inhibitor or a selective COX-1 inhibitor for use in a platelet inhibition treatment comprising the steps of: a. determining the expression level of one or more mi RNA(s) selected from the group consisting of miR-19b-1-5p, miR-1271, and miR-1537-5p, in a sample comprising platelet derived nucleic acids, b. comparing said expression level with a reference level, and c. determining the sensitivity or insensitivity of said subject for a treatment with said thromboxane A2 inhibitor or said selective COX-1 inhibitor based on the information obtained in step b. |
| priorityDate |
2015-05-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |