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publicationDate 2017-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3252033-A1
titleOfInvention Two-stage synthesis of n biaryl compounds
abstract Method comprising the method steps: a) reacting a naphthol which has a hydrogen ortho to the OH group with a chiral primary amine in the presence of water and with the addition of sodium hydrogen sulfite to form a secondary naphthylamine derivative, b) electrochemical coupling of the secondary naphthylamine derivative from a) using a solvent and a conducting salt with a phenol which has a hydrogen ortho to the OH group, so that either a direct coupling of the phenyl ring of the phenol in ortho position to the OH group with the naphthyl ring system in ortho position to the amino group, or - The oxygen of the pheol is coupled to the naphthyl ring system in ortho position to the amino group.
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