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filingDate 2016-01-26-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2017-12-06-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3250908-A1
titleOfInvention Multi-well fourier ptychographic and fluorescence imaging
abstract An imaging device for bright field Fourier ptychographic imaging and fluorescence imaging comprises a first fluorescence illumination source configured to provide excitation light of a first range of wavelengths to a transparent well; an optical system having a pair of objectives positioned oppositely; and an image sensor configured to receive light propagated through the optical system from the transparent well. The image sensor is configured to acquire a sequence of uniquely illuminated intensity measurements of light passing through a sample in the well based on sequential illumination at different illumination angles from a variable illumination source, and further configured to acquire a first fluorescence image of the sample based on light emitted by the sample in response to excitation light of the first range of wavelengths.
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