Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1224e3c07b7cc5684ee81d9e1e5ee15c |
classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-106 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-28 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-0002 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-108 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D257-02 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-101 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K33-244 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-547 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-18 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K49-10 |
filingDate |
2015-11-27-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_afdcd12810182d10c345c5272db8a219 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f9eae79b56033b7fd8191203780a63c9 |
publicationDate |
2017-10-04-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3223862-A1 |
titleOfInvention |
Metal complex formulations |
abstract |
The present invention relates to a method of preparation of formulations of lanthanide metal complexes of macrocyclic chelators which further comprise a small excess of free chelator. The method uses a solid phase-bound scavenger chelator to remove excess lanthanide metal ions, prior to the addition of a defined excess chelator. Also provided is a method of preparation of MRI contrast agents, together with solid-phase bound chelator meglumine salts useful in the methods. |
priorityDate |
2014-11-28-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |