abstract |
The present invention relates to a compound for use in the treatment and/or prevention of diseases or disorders wherein an inhibition of protein prenylation is required, which is alternatively chosen, among formulae (I) and (II), wherein R 1 is 2-pyridyl, 3-pyridyl or 4-pyridyl; R 2 represents formulae (III), (IV) and (V); and wherein R 5 and R 6 represent a hydrogen atom or a (C 1-4 )alkyl group; and R 7 represents an arylcarbonyl group, a heteroarylcarbonyl group, a heteroarylacetyl group, a (C 1 -C 4 )alkoxy-carbonylmethyl group,a formula (VI) group. Also disclosed are novel compounds of formulae (I) and (II). |