http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3202911-A1

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filingDate 2015-09-29-04:00^^<http://www.w3.org/2001/XMLSchema#date>
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publicationDate 2017-08-09-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3202911-A1
titleOfInvention Method for determining undifferentiated state of pluripotent stem cells by culture medium analysis
abstract There is provided a method for easily determining an undifferentiated state of pluripotent stem cells without relying on the judgment of a skilled technician. The method includes: a step of evaluating an undifferentiated state of pluripotent stem cells based on a time-dependent change in a variation value of an extracellular metabolite contained in a culture medium in which the pluripotent stem cells are cultured, wherein the extracellular metabolite is at least one selected from a group consisting of L-glutamic acid, L-alanine and ammonia.
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