abstract |
The present invention relates to compositions of virus-like particles for the introduction of RNA interference (RNAi) inducing molecules into eukaryotic cells and to methods for cell type specific transduction of a plurality of eukaryotic cells with RNAi-inducing molecules. Furthermore, the present invention relates to methods for diagnosis, prevention and / or treatment of diseases or disease states, which is associated with an increased expression rate of at least one endogenous gene and / or with the undesired expression of at least one endogenous gene and / or foreign nucleic acids, in particular viral nucleic acids , |