| Predicate |
Object |
| assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_50eb752940fa4aa36756a6bc9f6f3504 |
| classificationCPCAdditional |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2333-475
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N2800-52 |
| classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-57419
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-04
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/G01N33-74
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K38-179
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P35-00 |
| classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/G01N33-574 |
| filingDate |
2015-09-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_54e26599697c339c3a7a9169043255d4
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_dd291f5dff1a5123316cd09e78f63771
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_558bc783c72fb3b6e97354197be183c8 |
| publicationDate |
2017-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber |
EP-3194974-A1 |
| titleOfInvention |
Predictive and prognostic biomarkers related to anti-angiogenic therapy of metastatic colorectal cancer |
| abstract |
The present invention provides methods for treating metastatic colorectal cancer comprising identifying subjects who will respond favorably to anti-VEGF therapy. According to certain aspects of the invention, subjects are identified based on their expression level of VEGF-A. Favorable response to anti-VEGF therapy is indicated by elevated expression levels of VEGF-A. Also disclosed herein is the use of VEGF-A as a marker for identifying metastatic colorectal cancer- bearing subjects who are expected to have better relative survival outcomes to an anti-VEGF therapy. |
| isCitedBy |
http://rdf.ncbi.nlm.nih.gov/pubchem/patent/US-11382955-B2 |
| priorityDate |
2014-09-16-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type |
http://data.epo.org/linked-data/def/patent/Publication |