http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3194396-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_1c89ce4d9ac03f9acd8ddede1162f94d |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P25-00 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K45-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C07D471-04 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D471-04 |
| filingDate | 2015-09-14-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_1950059b0e285ae2d786fc594425402e http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_ff0063a2af8cb1e2e15575fd1d0d7542 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_d7b7aaf9795d9eeee9ae5a96c9db65b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_268fa1aa60a717130083ba0bfe457e8e |
| publicationDate | 2017-07-26-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3194396-A1 |
| titleOfInvention | Diazine-fused amidine compounds as bace inhibitors, compositions, and their use |
| abstract | In its many embodiments, the present invention provides certain C-6 spirocarbocyclic iminothiadiazine compounds, including compounds Formula (I) or a tautomer thereof, and pharmaceutically acceptable salts of said compounds and said tautomers, wherein R 1A , R 1B , R 2 , R A , ring A, R A , m, L 1 , R L , ring C, R C , and p are as defined herein. The novel compounds of the invention are useful as BACE inhibitors and/or for the treatment and prevention of various pathologies related thereto. Pharmaceutical compositions comprising one or more such compounds (alone and in combination with one or more other active agents), and methods for their preparation and use, including for the possible treatment of Alzheimer's disease, are also disclosed. |
| priorityDate | 2014-09-19-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
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