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publicationDate 2017-07-05-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3186399-A1
titleOfInvention Methods for rapid and sensitive detection of hotspot mutations
abstract Methods that rapidly, sensitively, and specifically detect mutations in IDH1/2 and the TERT promoter employ amplification of particular portions of the genes that experience frequent and exquisitely localized mutations. The ability to distinguish between sequences that differ only by one nucleotide and which may be present in very low ratios is essential for such an assay.
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