http://rdf.ncbi.nlm.nih.gov/pubchem/patent/EP-3167913-A1
Outgoing Links
| Predicate | Object |
|---|---|
| assignee | http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_79063e2752c3df3fc98fac171f0ff74c |
| classificationCPCAdditional | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2533-54 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N2502-1323 |
| classificationCPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0062 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0698 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L27-60 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C12N5-0629 |
| classificationIPCInventive | http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-24 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-38 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61L27-60 |
| filingDate | 2015-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| inventor | http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_334219e3728907be9aae44d891d797b8 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_07e2a7ad187852973d7546154caf9649 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_fefa83fd4cc64056aa93a21955ebcc05 |
| publicationDate | 2017-05-17-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| publicationNumber | EP-3167913-A1 |
| titleOfInvention | Method for making three-dimensional cultured skin model including dermis and epidermis, and three-dimensional cultured skin model made thereby |
| abstract | The present invention relates to a method for preparing a three-dimensionally cultured skin model comprising dermis and epidermis, which comprises: a step of preparing the dermis using a composition comprising murine fibroblasts; and native collagen or a combination of native collagen and atelocollagen; and a step of forming the epidermis using keratinocytes. Also, the present invention relates to a three-dimensionally cultured skin model which comprises: a dermis prepared by a composition comprising murine fibroblasts, native collagen, or a combination of native collagen and atelocollagen; and epidermis formed from keratinocytes. The three-dimensionally cultured skin model of the present invention may be used widely in toxicity and efficacy experiments of medicines or cosmetics, and in the field of alternative experiments for animal experiments since the three-dimensionally cultured skin model is excellent in formation and differentiation of dermis and epidermis using murine 3T3 cells for preparing the skin model and a mixture of atelocollagen and native collagen, and has a structure similar to the human skin layer by inhibiting dermal contraction and collagen degradation in the dermis. |
| isCitedBy | http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107267441-A http://rdf.ncbi.nlm.nih.gov/pubchem/patent/CN-107267441-B |
| priorityDate | 2014-07-09-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
| type | http://data.epo.org/linked-data/def/patent/Publication |
Incoming Links
Total number of triples: 34.