Predicate |
Object |
assignee |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentassignee/MD5_26bb5026c40daea34b175c27c42c7884 |
classificationCPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-0046 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K31-496 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-34 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K47-10 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0029 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P27-16 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61K9-06 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0023 http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61L2-0017 |
classificationIPCInventive |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/C07D215-56 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K31-497 http://rdf.ncbi.nlm.nih.gov/pubchem/patentipc/A61K9-16 |
filingDate |
2015-07-01-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
inventor |
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_daa318c663a54250bf8ed7ea65e087e0 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_51756d0b18f8d030f8f3754200041ab6 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_252c1639cf212077d916a06ea6746916 http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_f31178bad6f025e0a8844d6cc7edc7ba |
publicationDate |
2017-05-10-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
publicationNumber |
EP-3164115-A1 |
titleOfInvention |
Sterilization of ciprofloxacin composition |
abstract |
Disclosed herein are methods of making sterilized ciprofloxacin compositions. In some embodiments, the method includes the steps of: (a) forming an aqueous suspension comprising ciprofloxacin particles; (b) heating the aqueous suspension comprising ciprofloxacin particles at a temperature range of from about 100 °C to about 120 °C; and (c) allowing the aqueous suspension comprising ciprofloxacin particles to cool down. Also described herein are otic formulations containing ciprofloxacin formed by the disclosed methods, and therapeutic use of such otic formulation for providing sustained release of ciprofloxacin into the ear for treating various otic disorders and conditions. |
priorityDate |
2014-07-03-04:00^^<http://www.w3.org/2001/XMLSchema#date> |
type |
http://data.epo.org/linked-data/def/patent/Publication |