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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/C08B37-0045
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http://rdf.ncbi.nlm.nih.gov/pubchem/patentcpc/A61P37-04
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filingDate 2015-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
inventor http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_12ed8f48be28cb27c05d06ea1f001382
http://rdf.ncbi.nlm.nih.gov/pubchem/patentinventor/MD5_013e24986bd9076dec352732020fee87
publicationDate 2017-03-15-04:00^^<http://www.w3.org/2001/XMLSchema#date>
publicationNumber EP-3140324-A1
titleOfInvention O-acetylated high molecular weight polygalacturonic acids and their use as vi polysaccharide vaccine
abstract The instant disclosure provides O-acetylated high molecular weight polygalacturonic acids or pharmaceutically acceptable salts thereof, having at least one of: (a) a molecular weight greater than 1 x 106 Da; (b) a degree of mefhylation less than about 10% per mole; and (c) an intervening rhamnose content ranging from about 2% to about 15% per mole, useful as a synthetic immunogenic Vi antigen. The instant disclosure further provides methods of preparing an O-acetylated high molecular weight polygalacturonic acid or pharmaceutically acceptable salt thereof of, pharmaceutical compositions and/or vaccine compositions comprising the same, and methods of immunization using any of the foregoing.
priorityDate 2014-05-08-04:00^^<http://www.w3.org/2001/XMLSchema#date>
type http://data.epo.org/linked-data/def/patent/Publication

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